Duncan Hamish Wright

Company: Schrodinger Inc

Job title: Vice President, Translational Science

Seminars:

SGR-2921, A Clinical Stage CDC7 Inhibitor, Enhances DNA Damage, Replication Stress and Apoptosis in AML Tumor Models 11:30 am

• Schrodinger’s physics-based technology facilitated the discovery of highly potent CDC7 inhibitors, including SGR-2921 which demonstrates strong anti-leukemic activity in various preclinical models of AML mediated through mechanisms that exploit DNA damage and ultimately cell death, which are secondary to enhanced replication stress • Compelling preclinical activity across various molecular genetic contexts of AML and…Read more

day: Day Two Track B