Driving Mechanistic Advances in Next-Generation DDR Inhibitors

Validate Novel Targets & Utilize Biomarker-Driven Combination Strategies to Accelerate the Development of Durable, Selective & Low-Toxicity DDR Therapeutics

Returning to Boston for its 9th year, the DDR Inhibitors Summit is the definitive industry forum for drug developers advancing DNA Damage Response (DDR)-targeted therapies. With PARP inhibitors now clinically validated, the field is rapidly evolving to explore novel DDR targets like ATR, CHK1/2, DNA-PK, and WEE1, alongside smarter biomarker strategies and combination approaches.

This year’s summit is your opportunity to stay ahead of the curve. Across three content-rich days, you’ll uncover translational breakthroughs, hear from biotech innovators & academic pioneers, and gain strategic insights to overcome resistance, enhance selectivity, and accelerate clinical success. With the DDR landscape rapidly expanding, now is the time to connect, collaborate, and shape the future of targeted oncology.

The DDR field is approaching a critical point of validation, going beyond the first-generation PARP drugs, with many new agents in early development. Year on year, this conference brings together key leaders and decision-makers striving to advance this field to the benefit of underserved patients.

Jon Hollick, Managing Director & Head of Research, Breakpoint Therapeutics

Breakpoint

This meeting provides practical knowledge of the opportunities and challenges in moving therapeutic concepts from basic research to clinical trials and patient benefit.

Eric Brown, Associate Professor & Scientific Consultant, University of Pennsylvania

University of Pennsylvania

The most important thing to me was being able to meet people working in essentially all areas of the drug development pipeline. I learned a lot and substantially expanded my network.

Grant Frost, Co-founder & Chief Scientist, Riptide Therapeutics

Riptide Therapeutics

Explore the Full Event Guide

  • 30+ expert speakers from leading biopharma, biotech, and academia
  • 3 days of exclusive content, including a dedicated Biomarker Focus Day
  • 90+ attendees focused exclusively on DDR-targeted drug development
  • 1 Scientific Poster Session to showcase your latest research
  • Unmissable sessions on enhancing patient stratification, optimizing combination strategies & overcoming resistance
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What To Expect

90+

DDR-Focused Attendees

24+

Expert Speakers

12+

Hours of In-Person Networking

3

Days of Expert Insights & Exclusive Content

2

Brand New Sessions on Funding

Attending Companies Include

Viewing poster
Explore the Agenda

Hear the latest industry breakthroughs and gain exclusive insights during our packed agenda, interactive roundtables, and panel discussions.

Explaining poster
Partner With Us

Position yourself alongside other leading solution providers to ensure your brand is at the heart of biopharma deals.

poster session socialising
Join DDR Experts

Be part of the hottest conversations with like-minded attendees spanning all stages of drug development and make critical connections during our dedicated networking sessions.