Unveiling DNA breaks through direct STRIDE assays for precision in pre-clinical and clinical development of DDR inhibitors.
Time: 2:30 pm
day: Day One Track B PM
Details:
- The importance of direct DNA breaks detection in investigation of MoA and PD effects of DDR inhibitor
- Introduction to STRIDE platform with examples of its applications in pre-clinical and patient-derived samples
- New quantitative, functional assays to study the status of homologous recombination repair in tumor biopsies