Eric J. Brown

Company: University of Pennsylvania & Aprea Therapeutics

Job title: Associate Professor & Scientific Consultant

Seminars:

Roundtable Feedback Panel 3:00 pm

Following the separate roundtable discussions, this session is dedicated for the roundtable leaders to share insights, outcomes, and further questions raised on each table This will be a panel format taking audience questions to close off the day Building on earlier talks about oncogenic stress, ssDNA gaps, and clinical trial optimization, this round-up will leave…Read more

day: Pre-Conference Biomarker Focus Day PM

Exploring Oncogenic Stress & DNA Repair Defect as Biomarkers for DDR Therapies 9:00 am

Understanding how both replication stress caused by oncogenic mutations and DNA repair mutations increase reliance on cell cycle checkpoint regulators and DNA repair proteins to maintain genome integrity Assessing how inhibition of these cell cycle checkpoints and DNA repair proteins in the context of such cancer-associated mutations leads to more selective genome destabilization and killing…Read more

day: Pre-Conference Biomarker Focus Day AM