Single Stranded DNA Gaps Denotes Sensitivity to DDR Inhibitors, Identifies Effective Combination Therapies & Screens for Novel DDR Inhibitors
Time: 9:30 am
day: Pre-Conference Biomarker Focus Day AM
Details:
- Assessing how ssDNA Gaps in cancer are a rapid, reliable, and more robust biomarker than HRD score to stratify patients likely to benefit from DDR-targeted cancer therapy
- Exploring the shift in the ssDNA Gap burden indicates DDR pathway(s) alteration
- Measuring ssDNA Gap burden identifies effective DDRi combinations and novel anticancer therapeutics
