Personalizing Radiotherapy: Deciphering DNA Damage Response Dependent & Independent Mechanisms of ATR Inhibition
Time: 1:50 pm
day: Day One
Details:
- Reviewing the unmet need in early stage and advanced triple negative breast cancer for new strategies to overcome therapeutic resistance, and discuss opportunities to exploit unique DNA damage responses to photon versus proton radiotherapy
- Exploring a novel role for ATR in mediating therapeutic resistance, independent of DNA damage
- Discussing the implications for optimizing ATR inhibitor clinical development and potential biomarkers of response
