Zakia BELAID-SANDAL
CEO/CSO Theranovir
Seminars
            Wednesday 28th January 2026
        
        Disrupting DDR Signaling by Targeting Leptin-Dependent NRP-1/ OBR with NOV2 to Overcome Resistance & Induce Chromosomal Instability
    
    
        
            2:15 pm
            
        
    
    • See how Theranovir are developed NOV2, a monoclonal antibody targeting the Leptin-dependent NRP-1/OBR complex involved in DDR signaling and nuclear translocation
• Sharing preclinical data demonstrating NOV2’s ability to induce chromosomal instability, including centromere disruption and telomere shortening
• Exploring NOV2’s potential to overcome resistance and relapse, and its future use in combination with PARP inhibitors
 
					