Ivan Ahel
EP Abraham Professor of Chemical Pathology University of Oxford
Seminars
Wednesday 28th January 2026
Expanding Beyond PARP to Unlock Novel Hydrolase Pathways for DDR Drug Discovery
9:45 am
• Illustrating the complexity of PARP-dependent pathways and highlighting underexplored hydrolases, regulators, and effectors with therapeutic potential
• Showcasing emerging early-stage discovery programs targeting alternative hydrolases as biomarkers and drug targets
• Encouraging broader exploration of DDR biology to avoid “PARP tunnel vision” and inspire innovation in next-generation DDR therapies
