Wael Jdey

Wael Jdey

Company: Onxeo

Job title: Head of In Vitro Oncology Research & Innovation Group


A New Generation of DDR Targeting Drugs: DNA Decoy Agonists of DNAPK & PARP1 4:30 pm

The DDR pathway is made up of well-orchestrated machinery, with redundant pathways that could take over when one enzyme/pathway is inhibited commonly leading to acquired resistance to small molecules inhibitors Onxeo developed a cutting-edge new technology to trap DDR proteins and abrogate the DNA repair machinery to trap and hyperactivate DDR enzymes, inducing a false…Read more

day: Day One

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