Geoffrey Shapiro

Company: Dana-Farber Cancer Institute

Job title: Director, Early Drug Development Center

Seminars:

Panel Discussion: DDR Inhibitors & the Immune Response Interface 12:15 pm

DNA damage checkpoint activation, inducing the expression of antimicrobial peptides and activating immune cell receptor ligands: what are the ways DDRis impact these immune responses Which pathways within DDR are involved in immune signalling? DNA damage and chronic inflammation: what is the link?Read more

day: Day One

Effects of Polymerase Theta Inhibition On the DDR-Deficient Immune Microenvironment 11:45 am

What pathways drive immune cell infiltration following polymerase theta inhibition? Is an immune response required for maximal efficacy of polymerase theta inhibitors? How can polymerase theta-induced immune responses be augmented further to improve anti-tumor efficacy?Read more

day: Day One