Closing Panel Discussion: Future Directions for DDRi
Time: 5:00 pm
day: Day Two
- What is the current status of DDRi combination with IO
- Thoughts and rationalizing on potential best outcomes DDR-DDR combos
- Reviewing the various combination approaches and new targets coming in – thought experiment based on pathway
- What are the combinations and new targets that are going to push the field forward in a durable and effective way?
- Designing for approval in monotherapy vs comb therapy?
- PARP combination directions
- How far to take monotherapies?
- How can we be equally successful with PARP in other cancer types?
- What makes DDRis so powerful?
- Advice on how to take novel targets into the clinic?
- Where is this field going?