Shridar Ganesan
Director, Center for Molecular Oncology Perlmutter Cancer NYU Langone Health
Seminars
Thursday 29th January 2026
Roundtable Discussion: Challenging Dogma & Re-examining DDR Science to Truly Improve Patient Outcomes
4:30 pm
• Reflecting on why preclinical mechanisms often fail in the clinic and exploring new ways to rethink PARP inhibitor mechanisms and dosing strategies
• Debating whether current success metrics in DDR drug development align with meaningful patient outcomes and explore shifting the focus to long-term benefit and resistance avoidance
• Sharing cross-disciplinary perspectives on how biomarkers, experimental tools, and trial design innovations can advance precision medicine
