Bonnie Dougherty

Bonnie Dougherty

Company: Tempus Labs

Job title: Computational Systems Biologist


A Transcriptomic Model of Homologous Recombination Deficiency in a Real-World Pan-Cancer Cohort 3:30 pm

Gene expression can be used to accurately predict HRD-status across solid tumor cohorts This transcriptomic model, HRD-RNA, enriches for samples with biallelic loss in BRCA1/2 and other genes in the homologous recombination pathway Cohorts, outside traditional BRCA-associated cohorts, have samples with biallelic loss of BRCA1/2 and samples predicted HRD+, suggesting new avenues for HRD targeted…Read more

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