Understanding Connections Between Immune Response & DNA Damage Defects in Chronic Lymphocytic Leukaemia ( CLL) as a Disease Model

Time: 4:30 pm
day: Day Two


  • Exploring how DNA damage defects in CLL lead to the accumulation of DNA damage and activation of nucleic acid sensing pathways
  • Understanding why activation does not lead to the induction of INFI and immune responses in all tumors
  • Delve into how the integrity of sensing pathways and the immune cells’ exhaustion may hamper anti-tumor immunity and this provides an opportunity for therapeutic intervention