Effects of Polymerase Theta Inhibition On the DDR-Deficient Immune Microenvironment

Time: 12:30 pm
day: Day One


  • What pathways drive immune cell infiltration following polymerase theta inhibition?
  • Is an immune response required for maximal efficacy of polymerase theta inhibitors?
  • How can polymerase theta-induced immune responses be augmented further to improve anti-tumor efficacy?